Table 1.

Desensitization: time constants (s) from excised patches

20 s pulse	τ1	%	τ2	%	τ3	%	τ4	%	τ(W)	n
α1β2	0.024 ± 0.002	12 ± 6	0.13 ± 0.01	18 ± 15	1.04 ± 0.47	57 ± 14	4.0 ± 1.0	10 ± 4	1.1 ± 0.4	4
+GABARAP	0.024 ± 0.001	14 ± 9	0.36 ± 0.18	23 ± 18	1.15 ± 0.69	42 ± 18	3.5 ± 1.0	19 ± 6	1.1 ± 0.2	4
αβtan+α1	0.024 ± 0.001	26 ± 3	0.22 ± 0.13	20 ± 17	0.62 ± 0.22	39 ± 18	4.9 ± 1.9	14 ± 6	1.0 ± 0.5	3
α1β2γ2S 1:1:0.5	0.006 ± 0.003	8 ± 5	0.17 ± 0.17	26 ± 23	1.27 ± 0.79	39 ± 19	3.9 ± 1.6	24 ± 17	1.5 ± 0.8	4
+GABARAP	0.025 ± *	2 ± *	0.39 ± 0.16	4 ± 5	1.14 ± 0.26	50 ± 31	6.0 ± 1.5	30 ± 13	3.1 ± 1.7	4
α1β2γ2S 1:1:1	0.012 ± 0.008	8 ± 7	0.27 ± 0.11	19 ± 9	1.27 ± 0.39	55 ± 14	5.7 ± 3.1	14 ± 13	1.9 ± 0.7	7
α1β2γ2S 1:1:10					1.41 ± 0.33	33 ± 26	6.3 ± 2.4	44 ± 11	4.4 ± 1.9	5
+GABARAP					1.10 ± 0.46	45 ± 17	7.2 ± 2.4	38 ± 14	4.4 ± 1.5	7
αβtan+γ2S					1.07 ± 0.03	21 ± 3	6.2 ± 1.6	70 ± 7	5.7 ± 1.6	5
+GABARAP					1.38 ± 0.63	19 ± 9	5.2 ± 1.1	68 ± 12	4.3 ± 1.1	4
αβtan+γ2L					1.16 ± 0.27	19 ± 8	7.2 ± 0.7	56 ± 15	5.7 ± 0.7	4