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. Author manuscript; available in PMC: 2008 Oct 31.
Published in final edited form as: Biomacromolecules. 2008 Jul 30;9(9):2322–2328. doi: 10.1021/bm800269h

Figure 1.

Figure 1

Pulse sequence shown is used to measure spectrally resolved diffusion data. The first 180° rf pulse inverts the magnetization. The inversion recovery time td is selected to minimize the water signal that is available at the initiation of the PGSE experiment with the 90° pulse. The first gradient dephases the protons, the 180° pulse between the gradients is used to reverse the precession of the protons, and the second gradient refocuses the magnetization. The rf coil detects the echo signal at the echo time, TE. The Fourier transform of this signal provides the spectrum for the sample. The signal decay as a function of an increasing gradient pulse amplitude contains the information for diffusion measurements.