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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Epilepsia. 2008 May 21;49(10):1777–1786. doi: 10.1111/j.1528-1167.2008.01674.x

Fig. 2. Antiictigenic effects of retigabine under conditions of the rapid kindling.

Fig. 2

Afterdischarge threshold (upper, left Y-axis) and behavioral seizure score in response to threshold stimulation (bottom, right Y-axis) before (-20 min on X-axis) and at different time points after rertigabine administration to kindled animals. Retigabine (RTG) was injected at a dose of 2.5 mg/kg to P14, and 5 mg/kg to P21 and P35 rats. Data are presented as Mean ± SEM. Asterisk- p < 0.05 vs. “−20 min”: repeated measure ANOVA + Bonferroni test for afterdischarge threshold; Friedman + Wilcoxon test for behavioral seizure score.