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TBPB does not occupy central D2 dopamine receptors at doses that produce antipsychotic-like effects. Representative PET images showing [18F]fallypride binding in rat striatum after vehicle (A–C) or a dose of TBPB (100 mg/kg, s.c.) (D), haloperidol (0.1 mg/kg, s.c.) (E), or haloperidol (1.0 mg/kg s.c.) (F) pretreatment. Single slices of the images that were summed over the duration of the scans are depicted. The slice thickness is 0.08 cm.
