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. Author manuscript; available in PMC: 2009 Oct 3.
Published in final edited form as: J Mol Biol. 2008 Jul 3;382(2):342–352. doi: 10.1016/j.jmb.2008.06.080

Table 1.

Parallel and unique mutations accumulated in persistent genotypes between passage 10 and passage 25.

Strain Substitutions
Parallel substitutions
PA U50G, A1377G, C3978A, U4434G
PB U50G, G253A, C4003A, U4434G
PC U50G, C4003A, U4434G
PD U50G, G253A, C3878A, C4003A
Unique substitutions
PA None
PB G10337K,
PC A822R, U3750K
PD U1438Y, C2605A, G2798A, A3169M, A10523G