Average RBC velocities in 4T07 tumors treated with LTSL-DOX-HT (n=7) and LTSL-HT (n=5). The velocity was measured at 0.5 hr before, at 0, 6 and 24 hrs after the treatment. Error bars, SEM; *, p<0.05, when comparing data between LTSL-DOX-HT and LTSL-HT groups. In addition, the velocities at 0, 6, and 24 hrs were significantly less than that before the treatment in the LTSL-DOX-HT group (p<0.05), whereas the decrease in RBC velocity after the treatment was statistically significant (i.e., p<0.05) only at 24 hrs in the LTSL-HT group.