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. 2006 Jun 20;11(13):661–668. doi: 10.1016/j.drudis.2006.05.002

Table 1.

Sample instruments for assembling chemical microarray reactions

Process Device Technology Manufacture Specificity
Arrayer or spotter QArray microarrayer Solid pin http://www.genetix.com Contact nanoliter pin printing, higher coefficient of variation (CV), humidity control, fast, great for making multiple chips with large chemical library.
NanoPrint™ microarrayer Solid pin http://www.arrayit.com Contact nanoliter pin printing, humidity control, automatic plate handler, higher CV, fast, great for making multiple chips with large chemical library.
Manual arrayer and pin tool Solid pin http://www.vp-scientific.com Contact nanoliter pin printing, higher CV, great for research.
Gilson Constellation Solenoid dispensing http://www.gilson.com Non-contact printing, slow, 5–500 nl, low CV. Similar machines are available in most pharmaceutical laboratories.
ArrayJet Inkjet printing http://www.arrayjet.co.uk Non-contact printing, μl range, low CV, good for small chemical library printing.
Piezorray Piezo printing http://las.perkinelmer.com Non-contact printing, slow, pl to nl range, low CV.
Echo 550 Acoustic http://www.labcyte.com With potential for nl range spotting.
ATS-100 Acoustic http://www.edcbiosystems.com With potential for nl range spotting.
Activator Sprayer Aerosol http://www.reactionbiology.com Fast activation, low reagent consumption.
Gel caster SDS-page gel apparatus http://www.bio-rad.com Available in all biology laboratories.
Imager and data analysis NovaRay® Charge-coupled device (CCD) camera imager http://www.alphainnotech.com Fluorescence intensity, read microarray and plate, 4 μm resolution.
ViewLux™ CCD camera imager http://www.perkinelmer.com Fluorescence polarization, fluorescence intensity, time-resolved fluorescence, luminescence and absorbance assays. Low resolution for high-density microarray.
GenePix® Laser scanner http://www.moleculardevices.com Fluorescence intensity, four lasers, 5–100 μm resolution, slide autoloader.
LS Reloaded™ Laser scanner http://www.tecan.com Read microarray and plate, fluorescence intensity, four colors, 4–40 μm resolution, adjustable angle of laser beam for dual color scanning.
Typhoon™ Laser scanner http://www4.amershambiosciences.com Applicable for fluorescence, luminescence and isotopic imaging, four colors, 10–100 μm resolution.
IsoCyte™ Laser scanner http://www.blueshiftbiotech.com A plate reader with four channel intensity, two channel anisotropy, but with potential of fluorescence intensity and polarization detection for microarray.