Table 3.

Stratified analysis for CCND1, P53 R72P, and CDK6 by gender and age

	Male			Female			Young Individual(Age ≤60)			Old Individual (Age>60)
	Control	Case	OR(95% CI) *	Control	Case	OR(95% CI) *	Control	Case	OR(95% CI) ‡	Control	Case	OR(95% CI) ‡
CCND1 P241P	82	81		65	63		79	83		68	61
GG	33	15	1	23	22	1	36	23	1	20	14	1
AG	39	43	2.55(1.08-6.04)	30	27	0.85(0.36-2.04)	31	40	2.08(0.95-4.57)	38	30	0.97(0.38-2.49)
AA	10	23	9.89(3.00-32.68)	12	14	0.84(0.29-2.48)	12	20	2.75(1.02-7.42)	10	17	2.67(0.83-8.58)
Dominant			3.51(1.56-7.93)			0.85(0.38-1.92)			2.26(1.09-4.71)			1.30(0.54-3.14)
Recessive			5.37(1.94-14.88)			0.92(0.36-2.40)			1.83(0.76-4.44)			2.72(1.00-7.36)
P for trend			<0.0001			0.729			0.030			0.127
P53 R72P	77	61		60	49		73	64		64	46
GG	37	36	1	31	26	1	33	36	1	35	26	1
GC	30	20	0.65(0.28-1.50)	23	22	1.15(0.50-2.64)	28	26	1.06(0.48-2.33)	25	16	0.59(0.24-1.46)
CC	10	5	0.63(0.17-2.42)	6	1		12	2	0.19(0.03-1.29)	4	4	0.83(0.13-5.42)
Dominant			0.65(0.30-1.41)			0.92(0.41-2.08)			0.85(0.40-1.81)			0.62(0.26-1.46)
Recessive			0.75(0.21-2.76)						0.19(0.03-1.22)			0.99(0.16-6.29)
P for trend			0.31			0.434			0.268			0.368
CDK6 3′UTR	80	77		62	52		75	75		67	54
CC	46	54	1	35	32	1	43	57	1	38	29	1
CT	29	20	0.64(0.29-1.43)	26	15	0.57(0.24-1.38)	29	15	0.44(0.19-0.98)	26	20	1.06(0.45-2.49)
TT	5	3	0.72(0.12-4.13)	1	5	7.75(0.76-79.39)	3	3	0.68(0.12-3.95)	3	5	3.17(0.58-17.32)
Dominant			0.65(0.30-1.41)			0.78(0.34-1.78)			0.46(0.21-1.00)			1.23(0.54-2.78)
Recessive			0.84(0.15-4.77)			9.50(0.96-94.52)			0.89(0.16-5.05)			3.09(0.59-16.07)
P for trend			0.33			0.743			0.095			0.344

^*Adjusted by age, ethnicity, smoking status(never, former, and current), and alcohol use

^‡Adjusted by age, gender, ethnicity, smoking status(never, former, and current), and alcohol use