. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: Cancer. 2008 Nov 1;113(9):2488–2495. doi: 10.1002/cncr.23854

Table 4.

Combined analysis for the number of unfavorable genotypes^* in cell-cycle control pathways

Risk (No. of unfavorable genotypes)	No. of controls	No. of patients	OR (95% CI)	P value
Low(1∼2)	37	5	Ref.
Medium (3)	56	39	5.01(1.74-14.40)	0.0028
High (4∼5)	39	43	6.18(2.14-17.86)	0.0008
P for the trend				0.002

Unfavorable genotypes: CCND1 P241P(AG/AA), P53 R72P (GG/GC), CDK4 3′UTR (AA/AC), P27 5′UTR (TT), CDK6 3′UTR(CC), STK15 F31I (AA),

Adjusted by age, gender, ethnicity, smoking status, and alcohol use

Abbreviations: CI = confidence interval; OR = odds ratio.