Table 2.
UGT1A9 and UGT2B7 alleles in various populations
| Gene | Allele | Frequencies |
|||||
|---|---|---|---|---|---|---|---|
| CA (n=94) | AfA (n=86) | AsA (n=83) | HA (n=87) | WA (n=133) | PNG (n=153) | ||
| UGT1A9 | 8G | 1 | 1 | 0.99 | 1 | 1 | 1 |
| 8A | 0 | 0 | 0.01 | 0 | 0 | 0 | |
| 98T | 0.99 | 1 | 0.99 | 0.99 | 1 | 1 | |
| 98C | 0.01 | 0 | 0.01 | 0.01 | 0 | 0 | |
| 766G | 1 | 1 | 0.99 | 1 | 1 | 1 | |
| 766A | 0 | 0 | 0.01 | 0 | 0 | 0 | |
| UGT2B7 | 211G | 1 | 1 | 0.91 | 0.98 | 1 | 1 |
| 211T | 0 | 0 | 0.09a | 0.02 | 0 | 0 | |
| 802C | 0.48 | 0.66 | 0.59 | 0.72 | 0.79 | 0.72 | |
| 802T | 0.52b | 0.34 | 0.41 | 0.28 | 0.21c | 0.28 | |
| 1192G | 1 | 1 | 1 | 1 | 1 | 1 | |
| 1192A | 0 | 0 | 0 | 0 | 0 | 0 | |
CA Caucasian-American; AfA African-American; AsA Asian-American; HA Hispanic-American; WA West African; PNG Papua New Guinean
a
P=0.05, Fisher's exact test, compared with HA
b
P<0.001, Fisher's exact test, compared with any other population
c
P=0.09, Fisher's exact test, compared with PNG