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. Author manuscript; available in PMC: 2008 Nov 3.

Published in final edited form as: J Biol Chem. 2006 Dec 1;282(7):5026–5036. doi: 10.1074/jbc.M609360200

Table 1. Comparison of reproductive organs and functions in male mice.

	Wild-type	Heterozygous	Homozygous
Body Weight (g)	29.1±3.1 (n=32) ^*	28.8±2.0 (n=38)^*	25.2±2.4 (n=32)
Testis/Body (mg/g)	7.00±1.19 (n=32)	7.10±1.35 (n=38)	7.71±1.72(n=32)
Epididymis/Body (mg/g)	2.52±0.44 (n=32)	2.48±0.38 (n=33)	2.47±0.39(n=28)
Seminal vesicular/Body (mg/g)	7.40±1.31 (n=32) ^*	7.63±1.28 (n=38)^*	5.28±1.58(n=32)
Penile/Body (mg/g)	0.77±0.13 (n=32) ^*	0.83±0.13 (n=36)^*	0.56±0.16(n=31)
Penile length (mm)	6.1±0.16 (n=5) ^*	6.1±0.19 (n=8)^*	4.4±0.33(n=8)
Sperm count (×10⁶/epididymis)	12.6±2.9 (n=10)	12.1±1.3 (n=10)	9.6±2.9(n=10)
Sperm motility	69.0±6.8 (n=10) ^*	66.2±2.5 (n=10)^*	47.7±8.8(n=10)
Serum Testosterone (ng/ml)	1.89±0.85 (n=17)^*	ND	3.62±0.46 (n=19)
Serum DHT (pg/ml)	175.4±56.3 (n=17)^*	ND	264.3±74.8 (n=19)

^*

vs homozygous (−/−), p<0.01