Table 5.
Distance from the 3′-end of genes to the next gene either for all known protein-coding genes with a gene to their 3′-end, or only those with a predicted G-quadruplex immediately to the 3′-end of the gene
| All known protein-coding genes | Class | Genes with G-PQS in 100 bases 3′ of TES | Enrichment |
|---|---|---|---|
| No. (%) | No. (%) | ||
| 21643 (100) | All with next gene | 561 (100) | |
| 1589 (7.3) | Overlapping (d ≤ 0) | 50 (8.9) | 1.21 |
| 20 054 (92.7) | Non-overlapping (d > 0) | 511 (91.1) | 0.98 |
| 1633 (7.5) | Near (0 < d ≤ 1000) | 97 (17.3) | 2.29 |
| 3376 (15.6) | Medium (1000 < d ≤ 5000) | 114 (20.3) | 1.30 |
| 15 045 (69.5) | Far (5000 < d) | 300 (53.5) | 0.77 |
| 3317 (15.3) | Very far (100 000 < d) | 51 (9.1) | 0.59 |
The data is binned into categories where the next gene overlaps the previous one, is within 1 kb (‘near’, shown in bold), from 1 to 5 kb away (‘medium’) or >5 kb away (‘far’). The subset where the next gene is >100 kb away (‘very far’) is also shown. Genes where there was no subsequent gene (because they were near a chromosome end) are not shown. Enrichment is calculated as percentage with G-PQS/% of all genes for each class.