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Cell cycle profiles of DNA-PKcs+/− and DNA-PKcs−/− cells following IR exposure. Parental HCT116 (WT), DNA-PKcs+/− (+/−), and DNA-PKcs−/− (−/−) cells were either left untreated or exposed to 5 Gy of IR and then analyzed for cell cycle distribution by propidium iodide staining and FACS analysis at the indicated times postirradiation. Error bars represent standard deviations. 8N, aneuploid.
