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Representative Western blot demonstrating the presence of HIF-1, TrxR, and Trx1, as well as β-actin, in cell lysates from Matrigel implanted into wild-type (WT) mice, Matrigel containing either nonsilencing control siRNA or siRNA specific to HIF-1 implanted into wild-type mice, and Matrigel implanted into mice with conditionally HIF-1 null myeloid cells. M, unsupplemented Matrigel samples; M+L, Matrigel-lactide samples.
