. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Gynecol Oncol. 2008 Jul 1;110(3):329–335. doi: 10.1016/j.ygyno.2008.05.008

Table 2.

Expanded phase^* = DLT

Stage	Cumulative Accrual	Maximum # of events^* to stop the study and consider the regimen feasible for phase III	Minimum # of events^* to stop the study and consider the regimen not feasible for phase III
1	20	4	8
2	40	11	12

Events = Dose limiting toxicity