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. 2008 Nov 14;4(11):e1000203. doi: 10.1371/journal.ppat.1000203

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Red spheres and green lines represent gp120 and gp41 subunits, respectively. (A) Possible modes of flexibility within any given Env spike (blue arrows). Cylindrical masks (blue) encompass the entire spike (B), the gp120 head region (C), or the gp41 leg region (D). Black arrows indicate translocation, rotation, and tilting applied during alignment.