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p21 is induced in human GH-producing pituitary adenomas. (A) (a–e) Immunohistochemistry of pituitary adenoma sections stained for p21 (brown). (f) Normal pituitary. (g) Breast carcinoma. (h) Pituitary carcinoma. (B) Confocal image of fluorescence immunohistochemistry for p21 and PTTG expression. Specimen was labeled with p21 antibody (red) and PTTG antibody (green). (C and D) Reciprocal p21 and PTTG expression in all pituitary tumor types (C) and in GH-secreting adenomas (D).
