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. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: FEBS Lett. 2008 Sep 5;582(23-24):3313–3319. doi: 10.1016/j.febslet.2008.08.019

Fig. 3.

Fig. 3

The pH-activity profiles for demethylation reactions of 3-meT in ssDNA and 3-meU in ssRNA by mFTO and hFTO. All reactions were run in triplicate at 16°C for 12 h. (A) Demethylation of 3-meT in the 15 mer ssDNA (1 nmol) by mFTO (0.05 nmol). (B) Demethylation of 3-meU in the 15 mer ssRNA (1 nmol) by mFTO (0.1 nmol). (C) Demethylation of 3-meT in the 15 mer ssDNA (1 nmol) by hFTO (0.5 nmol). (D) Demethylation of 3-meU in the 15 mer ssRNA (1 nmol) by hFTO (0.2 nmol).