Fig. 3.
Incorporation of serine and Cyc in a β-galactosidase/luciferase fusion reporter protein. Bars represent UAG read-through efficiency: M. barkeri tRNAPyl and either M. barkeri bacterial like SerRS (B-SerRS), M. barkeri methanogenic SerRSs (M-SerRS), E. coli SerRS (Ec-SerRS) or an empty expression vector (pET15 empty). As positive control, M. barkeri tRNAPyl and M. barkeri PylRS (Mb-PylRS) in the presence of Cyc was measured. Negative controls include measurements with either M-SerRS or B-SerRS without PylT.