Fig. 2.

Schematic model for a monomer–dimer protein including different kinds of subsytems: a aggregation level—the global system is decomposed into two subsystems, monomer (S_M) and dimer (S_D); b conformational level: the dimer subsystem (S_D) is decomposed into two conformational subsystems, S_R and S_T; c structural level—one conformation of the dimer is decomposed into two structural subsystems, and ; d microscopic level—the structural subsystems are decomposed resulting in four microscopic subsystems