Table 1.

Crude incidence rate and adjusted hazard ratios (95% CI) of cancer by diabetes status at baseline, ARIC, 1987–2000

	Number developing cancer	Person-years	Crude incidence rate	Age-, race- and sex-adjusted hazard ratio	95% CI	Fully-adjusted hazard ratio*	95% CI
Colorectal Cancer
No diabetes	157	137764	1.14	1		1
Diabetes	23	15023	1.53	1.18	(0.76, 1.84)	1.13	(0.71, 1.84)
Colon Cancer
No diabetes	110	137967	0.80	1
Diabetes	18	15033	1.20	1.31	(0.79, 2.16)	1.19	(0.70, 2.03)
Lung Cancer
No diabetes	215	138106	1.56	1		1
Diabetes	23	15066	1.53	0.80	(0.52, 1.24)	0.97	(0.62, 1.51)
Breast Cancer (Women)
No diabetes	305	75124	4.06	1		1
Diabetes	36	8023	4.49	1.07	(0.76, 1.52)	1.08	(0.75, 1.54)
Prostate Cancer
No diabetes	330	60374	5.47	1		1
Diabetes	34	6786	5.01	0.75	(0.53, 1.07)	0.71	(0.49, 1.03)

^*Adjusted for baseline age (continuous), race (white, black), body mass index (continuous), smoking status (current smoker, nonsmoker), pack years (continuous), ethanol intake (continuous), sport index (continuous), education (<high school graduate, ≥ high school graduate), sex and current hormone replacement therapy (male, female with no HRT, female with HRT).

ARIC = Atherosclerosis Risk in Communities Study

CI = Confidence Interval

HRT = Hormone Replacement Therapy