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. 2008 Nov 1;22(21):3037–3049. doi: 10.1101/gad.1682108

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Figure 3. — Intact node and midline in Smad1-null embryos. (A–J) Ventral views of the node region (arrowed) of whole-mount wild-type (wt) and Smad1^−/− embryos hybridized for Nodal, Dante, and Plunc expression. Included Uncx4.1 probe revealed number of formed somite pairs (sp). Note precocious Nodal expression in the LPM in a 1sp Smad1^−/− mutant (arrowheads). (K–N) Whole-mount (K) and section views (L–N) showing expression of Shh in wild-type and Smad1^−/− embryos. (fp) Floorplate; (hg) hindgut; (nc) notochord; (nd) node.