Table 1.
Cohort | na | Successful initiationb | Unsuccessful initiation | Ethanol preferencec | RRd | Extinctione | Prewaitf | Controlsg |
---|---|---|---|---|---|---|---|---|
1 | 8 | 6 | 2 | yes | 4 | 6 | yes | no |
2 | 6 | 3 | 3 | no | 4 | 3 | yes | no |
3 | 5 | 5 | 0 | no | 4 | 5 | yes | no |
4 | 12 | 5 | 1 | no | 20 | 11h | no | 6 |
5 | 9 | 5 | 0 | no | 20 | 9 | no | 4 |
6 | 12 | 8 | 4 | yes | 20 | 0 | no | no |
n = the number of rats that started the experiment
Successful initiation indicates the number of rats that met the criterion of consuming at least 0.3 g/kg of 10% ethanol in at least 4 of 5 consecutive days at the end of the initiation procedure.
Ethanol preference indicates whether that cohort underwent the pre- and post-initiation two bottle choice procedure.
RR = the final intended response requirement during the training period
Extinction = the number of rats that went through the extinction procedure at the end of the training.
Prewait indicates whether that cohort had an extra 45 min wait period in the chamber before the session began.
Controls = the number of rats that were never exposed to ethanol during the training.
Three controls were not included in the extinction analysis because they were not able to meet consistently the RR of 20.