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. Author manuscript; available in PMC: 2009 Jun 27.
Published in final edited form as: Cell. 2008 Jun 27;133(7):1149–1161. doi: 10.1016/j.cell.2008.05.048

Figure 1. Alignment and phylogeny of CALHM1.

Figure 1

(A) Sequence alignment of human CALHM3, CALHM2, and CALHM1, and of murine and C. elegans CALHM1. Conserved sequences are highlighted in blue and sequence conservation is mapped in a color gradient, the darkest color representing sequences with absolute identity and lighter colors representing sequences with weaker conservation. Boxes denote hydrophobic domains 1–4 (HD1–4). Stars, predicted N-glycosylation sites on human CALHM1.

(B) Phylogenetic tree including human CALHM1 (hCALHM1).