Table 1.
Distribution of descriptive characteristics and genotypes of participants by smoking status in Washington County, Maryland, 1989.
| Never Smokers | Former Smokers | Current Smokers | |||||
|---|---|---|---|---|---|---|---|
| MEN (n=3,871) | |||||||
| Participants* | 1,507 | 38.9 | 1,681 | 43.4 | 683 | 17.6 | |
| Age in 1989†‡ | 51.4 (50.7, 52.2) | 57.8 (57.2, 58.5) | 47.5 (46.5, 48.5) | ||||
| Education*‡ | <12 years | 264 | 17.5 | 450 | 26.8 | 168 | 24.6 |
| ≥12 years | 1,243 | 82.5 | 1,231 | 73.2 | 515 | 75.4 | |
| Number of Cigarettes per day† | --- | 25.6 (24.8, 26.4) | 24.5 (23.5, 25.5) | ||||
| COMT* | AA | 371 | 26.2 | 394 | 25.6 | 173 | 27.4 |
| AG | 734 | 50.3 | 804 | 52.2 | 317 | 50.2 | |
| GG | 310 | 21.9 | 341 | 22.2 | 142 | 22.5 | |
| DBH* | AA | 352 | 21.7 | 413 | 25.4 | 154 | 23.2 |
| AG | 696 | 42.9 | 770 | 47.4 | 331 | 49.9 | |
| GG | 412 | 28.2 | 441 | 27.2 | 178 | 26.8 | |
| MAO-A* | CO | 1,067 | 73.0 | 1,181 | 72.7 | 490 | 73.1 |
| TO | 395 | 27.0 | 443 | 27.3 | 180 | 26.9 | |
| WOMEN (n=6,188) | |||||||
| Participants | 3,829 | 61.9 | 1,342 | 21.7 | 1,017 | 16.4 | |
| Age in 1989†‡ | 54.4 (53.9, 54.9) | 55.1 (54.4, 55.9) | 48.7 (47.9, 49.6) | ||||
| Education*‡ | <12 years | 858 | 22.4 | 301 | 22.4 | 276 | 27.1 |
| ≥12 years | 2.971 | 77.6 | 1,041 | 77.6 | 741 | 72.9 | |
| Number of Cigarettes per day†‡ | --- | 17.3 (16.5, 18.1) | 19.3 (18.6, 19.9) | ||||
| COMT* | AA | 948 | 26.9 | 365 | 29.7 | 248 | 26.6 |
| AG | 1,817 | 51.6 | 593 | 48.2 | 468 | 50.2 | |
| GG | 757 | 21.5 | 272 | 22.1 | 216 | 23.2 | |
| DBH* | AA | 973 | 26.2 | 341 | 26.2 | 235 | 23.8 |
| AG | 1,812 | 48.8 | 616 | 47.3 | 493 | 50.0 | |
| GG | 928 | 25.0 | 345 | 26.5 | 258 | 26.2 | |
| MA0-A* | CC | 1,954 | 52.4 | 669 | 51.5 | 527 | 53.2 |
| TC | 1,475 | 39.6 | 515 | 39.7 | 390 | 39.4 | |
| TT | 298 | 8.0 | 114 | 8.8 | 73 | 7.4 | |
*
Number, percentage
†
Mean (95% CI)
‡
Indicates statistically significant (p ≤ 0.05) heterogeneity.