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. 2008 Nov;18(11):1752–1762. doi: 10.1101/gr.080663.108

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Figure 5. — Transposable elements are enriched for bound motifs and are associated with regulated genes. (A) Ratio between the fraction of motifs within a given repeat subfamily that is observed to be bound and the fraction of motifs that is expected to be bound. The x-axis represents the estimated age of the repeat subfamily (in millions of years). Two subfamilies of the B2 repeat associated with CTCF are highlighted: B3A and B2_Mm1a. (B) Gray bars indicate the percentage of ESR1 and POU5F1-SOX2 binding regions with and without repeats that are within 10 kb of a regulated gene. Expected levels based on a random set of genes are shown in white. An additional control is shown using a random sample of instances from the same repeat families. Error bars, 1 SD.