Table 2.
SNPs | Haplotypes | |||||
---|---|---|---|---|---|---|
Gene | Reference number | Position* | MAF** | Haplotype ID | Structure*** | Freq** |
CETP | rs17231506 | 5’F | 30 % | CETP-A | CGCACGGTCACCT | 20 % |
rs4783961 | 5’F | 49 % | CETP-B | TACCTGGTCGTCT | 14 % | |
rs17245715 | 5’F | 10 % | CETP-C | CACATATTCGTCT | 6 % | |
rs1800775 | 5’F | 49 % | CETP-D | CGTCTGGTCGCCT | 7 % | |
rs708273 | In2 | 30 % | CETP-E | TACCTGGTCGCGT | 6 % | |
rs12720922 | In2 | 18 % | CETP-Others§ | --------------------------- | 47 % | |
rs9939224 | In2 | 21 % | ||||
rs11076174 | In2 | 8 % | ||||
rs5883 | Ex9S | 5 % | ||||
rs4784744 | In10 | 35 % | ||||
rs1800774 | In12 | 35 % | ||||
rs289742 | 3’F | 13 % | ||||
rs12720917 | 3’F | 15 % | ||||
IL8 | rs4073 | 5’F | 48 % | IL8-A | ATC | 51 % |
rs2227307 | In1 | 47 % | IL8-B | TGT | 42 % | |
rs2227543 | In3 | 42 % | IL8-C | TGC | 3 % | |
IL8-Others§ | ----- | 3 % | ||||
PPARA | rs4253623 | In2 | 13 % | PPARA-A | GGGCAT | 29 % |
rs135543 | In2 | 29 % | PPARA-B | AAGTGT | 22 % | |
rs4253655 | In2 | 16 % | PPARA-C | GAGCGC | 11 % | |
rs4253699 | In2 | 20 % | PPARA-D | GGATGT | 9 % | |
rs4253701 | In2 | 10 % | PPARA-E | AAGTGT | 6 % | |
rs4253765 | In6 | 19 % | PPARA-Others§ | ------------ | 23 % | |
TLR4 | rs2770150 | 5’F | 27 % | TLR4-A | GCTGCACCGAGT | 27 % |
rs1927914 | 5’F | 36 % | TLR4-B | ACTGCACCGAGT | 22 % | |
rs7864330 | In1 | 6 % | TLR4-C | ACTGCACCCAGT | 14 % | |
rs1927911 | In1 | 28 % | TLR4-D | ATTACACCGAGT | 7 % | |
rs11536878 | In3 | 12 % | TLR4-E | ATTAAACCGGGT | 6 % | |
rs4986790 | Ex4N | 6 % | TLR4-F | ATGGCGTCGAGC | 5 % | |
rs4986791 | Ex4N | 5 % | TLR4-Others§ | --------------------------- | 18 % | |
rs7869402 | Ex4U | 4 % | ||||
rs11536889 | 3’F | 15 % | ||||
TLR4-17050 | 3’F | 16 % | ||||
TLR4-17723 | 3’F | 5 % | ||||
rs1927906 | 3’F | 10 % |
SNP position descriptions: F=flanking, Ex=exon, In=intron, N=non-synonymous, U= untranslated.
SNP minor allele frequencies (MAF) and probability-weighed haplotype frequencies among controls.
Haplotype structures in order of SNP list.
Others, a haplotype group that includes all other haplotypes with frequencies less than 5%.