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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: Am J Cardiol. 2008 Apr 9;101(12):1683–1688. doi: 10.1016/j.amjcard.2008.02.052

Table 2.

Single nucleotide polymorphisms (SNPs) and haplotypes

SNPs Haplotypes
Gene Reference number Position* MAF** Haplotype ID Structure*** Freq**
CETP rs17231506 5’F 30 % CETP-A CGCACGGTCACCT 20 %
rs4783961 5’F 49 % CETP-B TACCTGGTCGTCT 14 %
rs17245715 5’F 10 % CETP-C CACATATTCGTCT 6 %
rs1800775 5’F 49 % CETP-D CGTCTGGTCGCCT 7 %
rs708273 In2 30 % CETP-E TACCTGGTCGCGT 6 %
rs12720922 In2 18 % CETP-Others§ --------------------------- 47 %
rs9939224 In2 21 %
rs11076174 In2 8 %
rs5883 Ex9S 5 %
rs4784744 In10 35 %
rs1800774 In12 35 %
rs289742 3’F 13 %
rs12720917 3’F 15 %
IL8 rs4073 5’F 48 % IL8-A ATC 51 %
rs2227307 In1 47 % IL8-B TGT 42 %
rs2227543 In3 42 % IL8-C TGC 3 %
IL8-Others§ ----- 3 %
PPARA rs4253623 In2 13 % PPARA-A GGGCAT 29 %
rs135543 In2 29 % PPARA-B AAGTGT 22 %
rs4253655 In2 16 % PPARA-C GAGCGC 11 %
rs4253699 In2 20 % PPARA-D GGATGT 9 %
rs4253701 In2 10 % PPARA-E AAGTGT 6 %
rs4253765 In6 19 % PPARA-Others§ ------------ 23 %
TLR4 rs2770150 5’F 27 % TLR4-A GCTGCACCGAGT 27 %
rs1927914 5’F 36 % TLR4-B ACTGCACCGAGT 22 %
rs7864330 In1 6 % TLR4-C ACTGCACCCAGT 14 %
rs1927911 In1 28 % TLR4-D ATTACACCGAGT 7 %
rs11536878 In3 12 % TLR4-E ATTAAACCGGGT 6 %
rs4986790 Ex4N 6 % TLR4-F ATGGCGTCGAGC 5 %
rs4986791 Ex4N 5 % TLR4-Others§ --------------------------- 18 %
rs7869402 Ex4U 4 %
rs11536889 3’F 15 %
TLR4-17050 3’F 16 %
TLR4-17723 3’F 5 %
rs1927906 3’F 10 %
*

SNP position descriptions: F=flanking, Ex=exon, In=intron, N=non-synonymous, U= untranslated.

**

SNP minor allele frequencies (MAF) and probability-weighed haplotype frequencies among controls.

***

Haplotype structures in order of SNP list.

§

Others, a haplotype group that includes all other haplotypes with frequencies less than 5%.