Table 5.
Molecular pathways significantly (P ≤ 0.001) affected by ACN-GE in the liver
| Pathway Name | Number Measured on Pathway | Percent Changed | Z-Score |
|---|---|---|---|
| Pathways Significantly Up-Regulated | |||
| All pathways (reference) | 10,025 | 6.6 | 0 |
| Wnt Signaling | 269 | 14.9 | 4.8 |
| Pathways Significantly Down-Regulated | |||
| All pathways (reference) | 10,025 | 6.0 | 0 |
| Ribosomal proteins | 69 | 34.8 | 9.4 |
| Electron transport chain | 61 | 24.6 | 5.6 |
| Metabolism | 182 | 16.5 | 5.4 |
| Acute inflammatory response | 67 | 20.9 | 5.1 |
| Cholesterol biosynthesis | 12 | 41. 7 | 4.9 |
| Fatty acid beta-oxidation | 28 | 28.6 | 4.7 |
| Tricarboxylic acid cycle | 18 | 33.3 | 4.5 |
| Selenium metabolism-selenoproteins | 35 | 22.9 | 3.8 |
| Energy derivation by oxidation of organic compounds | 62 | 17.7 | 3.5 |