Table 1.

GCase Residual Activity in Tissues from kn-9H and neo-9h Mice

Genotype	Brain		Liver		Lung
	nmoles/h/mg 1	%2	nmoles/h/mg	%	nmoles/h/mg	%
WT (n=10–13)	28.83 (±1.37)	100	28.72 (±1.43)	100	43.13 (±4.5)	100
kn-9H/kn-9H (n=5)	2.78 (±0.14)	9.6	0.89 (±0.09)	3.1	0.73 (±0.12)	1.7
neo-9h/neo-9h (n=5)	2.50 (±0.16)	8.7	0.92 (±0.09)	3.2	0.70 (±0.22)	1.6
GCase null (n=5)	2.77 (±0.53)	9.6	0.88 (±0.119)	3.1	0.87 (±0.23)	2.0
D409H/D409H (n=9)	7.38 (±0.29)	25.6	3.29 (±0.16)	11.4	3.26 (±0.36)	7.6

¹GCase activity (±SEM)

²% WT activity.