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Both CD dimer 1 and dimer 5 decrease cross-linking efficiency, as evidenced by SDS/PAGE of cross-linking experiments with CS (Upper) and LDH (Lower). Lanes 1 and 10, molecular weight markers; lanes 2 and 3, enzyme alone; lanes 4 and 5, 1.0 μM enzyme + 7.0 mM BS; lanes 6 and 7, 1.0 μM enzyme + 0.7 mM dimer 5 + 7.0 mM BS; lanes 8 and 9, 1.0 μM enzyme + 0.7 mM dimer 1 + 7.0 mM BS.
