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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Arch Biochem Biophys. 2008 Apr 30;477(1):105–112. doi: 10.1016/j.abb.2008.04.032

Table 2.

SOD-like activity of the porphyrins studied.a

Porphyrin IC50, Mb log kcatc Ref.
MnIIITM-3-PyP5+ 6.5 × 10−7 6.61 [26]
MnIIBr8TM-3-PyP3+ ≤3.7 × 10−9 ≥8.85 this work
MnIIITM-4-PyP5+ 6.7 × 10−7 6.58 [26]
MnIIBr8TM-4-PyP4+ ≤5.6 × 10−9 ≥8.67 this work
Cu,Zn-SOD 1.3 × 10−9 ca. 9 [3537]
a

Conditions: 0.05 M phosphate buffer, 0.10 mM EDTA, pH 7.8, 40 μM xanthine, ~ 10 μM cytochrome c.

b

IC50 is the concentration of compound that causes a 50% inhibition of the cyt c reduction by O•−. The errors in IC50 are within 10%.

c

Error of ± 10 %.