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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Eur J Pharm Biopharm. 2008 Feb 14;69(3):861–870. doi: 10.1016/j.ejpb.2008.02.002

Figure 2.

Figure 2

Estimation of stratum corneum thickness (H) by the linear model (panel a) and by the simple (S-NL) and baseline corrected (BC-NL) non-linear models (panel b) for five subjects. [■] Experimental data points. Panel a: [–] prediction by LM including all experimental data; […] prediction by LM excluding a number of data points. Panel b: [–] prediction by BC-NL; […] prediction by S-NL model. The vertical lines mark the value of H estimated by: LM – all data points (panel a, solid line), LM – excluding data points (panel a, dotted line), the S-NL (panel b, dotted line) and the BD-NL (panel b, solid line).