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. 2008 Nov 28;4(11):e1000275. doi: 10.1371/journal.pgen.1000275

Figure 3. AML1 binding pattern on chromosome 19.

Figure 3

(A) Venn diagram representing the overlap of AML1 binding sites in U937-AE and U937-Mt cells with AML1/ETO binding sites on chromosome 19. Physical overlaps >20% were considered significant. (B) Representative screenshot of AML1 and AML1/ETO occupancy on chromosome 19. A window of 80 kb is shown. The two top lanes represent the AML1 binding profile in the control cell line U937-Mt and in U937-AE, respectively. The two bottom lanes represent AML1/ETO binding patterns obtained with anti-HA and anti-ETO antibodies. Asterisks indicate peaks identified by PeakPicker software.