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. 2008 May 28;2:38–43. doi: 10.2174/1874312900802010038

Table 1.

Cases With Primary SS and Lymphoma Treated with Rituximab

Author, Years N. of Pts Type of Lymphoma/Bone Marrow Involvement Ann Arbor Stage Response Other Concomitantly Immunosuppressive Agents
  Somer, 2003   1   Parotid gland MALT-type/no IE Yes   No
  Voulgarelis, 2004*   4

  1. Salivary gland MALT-type/yes*

  2. Nodal marginal zone/no*

  3. Pulmonary MALT-type/yes*

  4. Salivary gland MALT-type/yes*

 IV
IIE
IV
IV		 Yes
Yes
Yes
Yes

  1. CHOP

  2. CHOP

  3. CHOP

  4. CHOP
  Harner, 2004   1   Nodal marginal zone/Pulmonary MALT-type/no IIE Yes   No
  Ramos-Casals, 2004   2

  1. Ovarian MALT-type/yes

  2. Ocular MALT-type/yes

 IV
IV		 Yes
Yes

  1. CHOP

  2. Local radiotherapy
  Pijpe, 2005   1   Parotid gland MALT-type/no IE Yes   No
  Gottenberg, 2005#   2

  1. Digestive tract MALT-type/no#

  2. Salivary gland MALT-type/no#

 IE
IE		 Yes
No

  1. MP 500 mg x 4, HQ

  2. No
  Pijpe, 2005   7

  1. Parotid gland MALT-type/no

  2. Parotid gland MALT-type/no

  3. Parotid gland MALT-type/no

  4. Parotid gland MALT-type/no

  5. Parotid gland MALT-type/no

  6. Parotid gland MALT-type/no

 IE
IE
IE
IE
IE
IE
IE		 No
No
Yes
Yes
No
Yes
No

  1. No

  2. PDN 15 mg/day

  3. No

  4. No

  5. PDN 7.5 mg/day, MTX

  6. PDN 5 mg/day, AZA

  7. No
  Voulgarelis, 2006*   6

  1. Nodal marginal zone/no

  2. DLBCL/no

  3. Salivary gland MALT-type/yes

  4. *Nodal marginal zone/no*

  5. Pulmonary MALT-type/yes*

  6. Salivary gland MALT-type/yes*

 II
II
IV
IIE
IV
IV		 Yes
Yes
Yes
Yes
Yes
Yes

  1. CHOP

  2. CHOP

  3. CHOP

  4. CHOP

  5. CHOP

  6. CHOP
  Seror, 2007#   5

  1. Salivary gland MALT-type/no#

  2. Nodal marginal zone/yes

  3. Gastric/pulmonary MALT-type/no

  4. Gastric MALT-type/no#

  5. DLBCL/no

 IE
IV
IV
IE
III		 No
Yes
Yes
Yes
Yes

  1. No

  2. No

  3. Mini-CHOP

  4. HQ

  5. CHOP
  Present report   1   Parotid gland MALT-type/no IE No   High-dose steroids
*

There is some patients’ overlapping between the cases reported in Voulgarelis, 2004 and Voulgarelis, 2006.

#

There is some patients’ overlapping between the cases reported in Gottenberg, 2005 and Seror, 2007.

Abbreviations: pts, patients; MALT, mucosa-associated lymphoid tissue; CHOP, cyclophosphamide, doxorubicin, vincristine, prednisone; AZA, azathioprine; PDN, prednisone;MTX, methotrexate; MP, methylprednisolone; DLBCL, diffuse large B-cell lymphoma; HQ, hydroxychloroquine.