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. 2000 May 9;97(10):5083–5088. doi: 10.1073/pnas.97.10.5083

Figure 1.

Figure 1

UDG activity assays for substrate and product DNA constructs. Human UDG cleaves the glycosylic bonds of deoxyuridine and 4′S-dU but not the glycosylic bond of dΨU (see Methods). This is true even at high concentrations of UDG relative to DNA and over periods of weeks.