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. Author manuscript; available in PMC: 2009 Aug 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2008 Mar 15;230(3):269–275. doi: 10.1016/j.taap.2008.03.004

Dynamic lung compliance (Cdyn) and lung resistance (Rrs) of Balb/c mice after bronchoprovocation testing with methacholine aerosol *, significantly greater than air controls (Rrs, P=0.0007; Cdyn,P<0.0001). The values shown on the graphs are the group mean percentage decrease in Cdyn, or the group mean percentage increase in Rrs from baseline values (without methacholine challenge) ± SE at the highest concentration of methacholine tested, with experimental group size, N, represented as a bracketed number above the bar.

Dynamic lung compliance (Cdyn) and lung resistance (Rrs) of Balb/c mice after bronchoprovocation testing with methacholine aerosol *, significantly greater than air controls (Rrs, P=0.0007; Cdyn,P<0.0001). The values shown on the graphs are the group mean percentage decrease in Cdyn, or the group mean percentage increase in Rrs from baseline values (without methacholine challenge) ± SE at the highest concentration of methacholine tested, with experimental group size, N, represented as a bracketed number above the bar.