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. 2008 Nov;14(11):2430–2439. doi: 10.1261/rna.1189008

FIGURE 1.

FIGURE 1.

Pictograms of the U2-dependent (A) and U12-dependent (B) intron branch site consensus sequences using the data set described by Padgett and Burge (2003). In these pictograms, the size of the letter corresponds to the frequency in which that base is present at each position. The position labeled 1 (A,B) at the top is the predicted branch site residue. The numbers below the U12-dependent branch site pictogram (B) indicate the position of the residues in the P120 U12-dependent intron F. (C) Complementary base-pairing interactions between the U12-dependent branch site and the U12 snRNA anti-branch site. Numbered residues correspond to positions used in the mutational analysis. Adenosine 90 is the branch site residue used in this intron (Tarn and Steitz 1996).