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. Author manuscript; available in PMC: 2008 Nov 4.
Published in final edited form as: Arch Neurol. 2008 Apr;65(4):506–513. doi: 10.1001/archneur.65.4.506

Table 3. Summary of brain imaging findings.

Case Duration since symptom onset (years) Modality Key findings
III.2 2 MRI Marked asymmetrical frontal, temporal and parietal lobe atrophy predominantly affecting the right side. In the frontal lobes there is greater atrophy affecting the inferior frontal regions than the frontal convexities, although the convexity sulci are wider bilaterally. There is asymmetrical temporal lobe atrophy, with the whole right temporal lobe affected more than the left. There is also widespread right-sided parietal atrophy.
III.4 1 CT Asymmetrical generalized atrophy, affecting the right hemisphere more than the left.
III.9 1 MRI Mild diffuse atrophy with increased prominence of the parietal sulci.
III.11 1 MRI Asymmetrical frontal, temporal and parietal lobe atrophy predominantly affecting the left side. In the frontal lobes there is atrophy of the medial superior frontal and frontopolar regions, and involvement of the anterior cingulate gyrus. There is marked atrophy of the left temporal pole. The left superior temporal, middle and inferior temporal and fusiform gyri are significantly affected, with some atrophy of left amygdala and hippocampus. In the parietal lobes there is relatively selective atrophy of the left angular gyrus posteriorly.