Skip to main content
. 2000 May 2;97(10):5107–5112. doi: 10.1073/pnas.090588197

Figure 1.

Figure 1

(a) Schematic diagram of strand one 12-mer and strand two 14-mer RNAs that anneal to form the Watson–Crick base pairs indicated by solid vertical lines and the noncanonical base pairs indicated by vertical dots. The underlined U was brominated for crystallographic phasing and the italicized A and U are not base-paired. The four duplexes are numbered 101–130, 201–230, 301–330, and 401–430 with strand one from (1)01-(1)12 and strand two from (1)17-(1)30 for example. This numbering scheme corresponds to that used by Peterson and Feigon (5) for the NMR structure determination of the free RBE. The original numbering system used for the RRE denotes the G-G pair (6–24) as G48-G71 and the G-A (5–26) noncanonical pair as G47-A73. (b) Slab diagram of the RBE double helix indicating the continuous stacking of the core base pairs and the bulged nucleotides A21 and U25.