Skip to main content
. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Bioorg Med Chem. 2008 Jun 5;16(14):6696–6701. doi: 10.1016/j.bmc.2008.05.078

Table 3.

Purity of compounds determined by HPLC.

Compound Purity (%)a Purity (%)d Compound Purity (%)a Purity (%)d
2 98.9 94.8 11 97.5b 97.2
3 95.6 95.1 12 96.9 91.6
4 98.1 99.5 13 98.7c 99.4
5 99.6 99.6 14 96.4 97.8
6 95.4 98.3 15 98.4 98.4
7 98.0 100 16 97.1 96.6
8 91.8 91.2 17 96.4 99.5
10 100 98.4 18 99.1 100
a

Gradient of 88–95% of B in 22 min. Solvent A: 95% of acetonitrile/H2O and 0.045% of trifluoroacetic acid; Solvent B: acetonitrile/methanol/H2O = 85:10:5 and 0.045% of trifluoroacetic acid.

b

Gradient of 100% B in 30 min with same solvent system as described above.

c

Gradient of 90–100% B in 30 min with same solvent system as described above.

d

95% of acetonitrile/H2O in 30 min.