Table 2.
Clinical and demographic characteristics of recently diagnosed and established myelodysplastic syndrome (MDS) patients*
| Established patients % per survey (N = 4570) |
|||||||
| Characteristic† | Recently diagnosed patients (N = 670) | Survey 1 (n = 614) | Survey 2 (n = 664) | Survey 3 (n = 816) | Survey 4 (n = 789) | Survey 5 (n = 804) | Survey 6 (n = 827) |
| Patients per survey, n | |||||||
| Median (IQR) | 112 (66 to 149) | — | — | — | — | — | — |
| Median age at diagnosis, y (IQR) | 71 (65 to 80) | 72 (65 to 80) | 74 (67 to 80) | 74 (67 to 80) | 75 (68 to 81) | 74 (68 to 81) | 74 (67 to 80) |
| Male‡, % (95% CI) | 55 (52 to 59) | 57 | 51 | 51 | 54 | 54 | 55 |
| Duration of disease, mo | |||||||
| Median (IQR) | — | 16 (7 to 36) | 16 (8 to 37) | 13 (7 to 31) | 16 (7 to 36) | 16 (8 to 33) | 15 (7 to 34) |
| Minimum; maximum | 3; 240 | 3; 220 | 3; 169 | 3; 194 | 3; 172 | 3; 250 | |
| Secondary MDS§, % (95% CI) | 10 (8 to 12) | 12 | 12 | 9 | 8 | 7 | 7 |
| Suspected reason for secondary MDS‖, % (95% CI) | |||||||
| Chemotherapy only | 76 (66 to 86) | 58 | 67 | 55 | 60 | 80 | 74 |
| Radiation only | 7 (1 to 14) | 11 | 12 | 15 | 21 | 8 | 6 |
| Chemotherapy and radiation | 7 (1 to 14) | 11 | 4 | 8 | 0 | 0 | 2 |
| Chemical exposure | 3 (0 to 7) | 5 | 6 | 2 | 4 | 6 | 9 |
| Other | 6 (0 to 12) | 15 | 12 | 20 | 15 | 6 | 9 |
The total “n” listed at the heading of each established patients survey column includes recently diagnosed (ie, diagnosed in the previous 2 months) and established patients for whom this information was collected in that survey. Results for recently diagnosed patients were combined from across all six surveys and reported along with 95% CIs. IQR = interquartile range; — = not applicable; CI = confidence interval.
Characteristic at the time of the survey, excluding 14 patients with unknown duration of disease.
Excludes 1 recently diagnosed patient and 10 established patients with missing information on sex.
Excludes one recently diagnosed patient and three established patients with missing information on primary vs secondary MDS disease status.
Reported for patients with secondary MDS only (N = 68 recently diagnosed and N = 344 established patients). Excludes one recently diagnosed patient and two established patients with secondary MDS who had missing information on the suspected cause of disease.