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. 2008 Oct 28;105(44):16976–16981. doi: 10.1073/pnas.0802898105

Fig. 2.

Fig. 2.

B lymphopoiesis is impaired in GsαOsxKO mice. (A) Frequency of each lineage, shown as percentage of total marrow cells in postnatal day 10 bone marrow (n = 4). *, P < .005. (B) Gr-1+ myeloid cells and B220+ cells as a percentage of peripheral blood leukocytes at postnatal day 10 (n = 4). *, P < .005. (C) Number of splenic B220+ cells, as a percentage of the number of B220+ cells in WT littermates, is reduced in KO spleens at postnatal day 10 (n = 4). *, P < .001. (D) Percentage of bone marrow cells that are B220+/CD93+/IgM− (Left) or B220+/CD93+/IgM+ (Right) at postnatal day 8 (n = 10 WT or 7 KO). *, P < .05. (E) Percentage of B220+/CD19−/CD43+ prepro-B cells in bone marrow on postnatal day 8 (n = 6). (F) Percentages of pro-B (B220+/IgM−/CD43+) and pre-B (B220+/IgM−/CD43−) cells in bone marrow on postnatal day 8 (n = 3). *, P < .05.