Table 2.
IGF2 DMR methylation among individuals exposed to famine late in gestation and their unexposed, same-sex siblings
IGF2 DMR methylation | Mean methylation fraction (SD) |
Relative change exposed | Difference in SDs | P | |||
---|---|---|---|---|---|---|---|
Exposed (n = 62) | Controls (n = 62) | ||||||
Average | 0.514 | 0.045 | 0.519 | 0.036 | −0.9% | −0.12 | .64 |
CpG 1 | 0.460 | 0.044 | 0.464 | 0.048 | −0.9% | −0.09 | .68 |
CpG 2 and 3 | 0.462 | 0.039 | 0.471 | 0.039 | −1.7% | −0.21 | .46 |
CpG 4 | 0.602 | 0.085 | 0.612 | 0.073 | −1.5% | −0.12 | .30 |
CpG 5 | 0.529 | 0.060 | 0.531 | 0.060 | −0.3% | −0.02 | .77 |
P values were obtained using a linear mixed model and adjusted for age.