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. 2008 Oct 28;105(44):17187–17192. doi: 10.1073/pnas.0808207105

Fig. 1.

Fig. 1.

SRC-3−/− mice are lean with an increased insulin sensitivity and an improved lipid profile compared to SRC3+/+ mice (A) Body weight evolution of mice on either chow or HF diet (n = 8). (B) Serum glucose and insulin levels in mice fed an HF diet after a 6 h fasting (n = 8). (C) Serum glucose levels evolution during an i.p. glucose tolerance test performed after a glucose load (2g/kg) in chow or HF fed, overnight-fasted mice (n = 8). (D) Serum levels of total cholesterol (T-C), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), triglycerides (TG) and free fatty acids (FFA) in mice fed an HF diet (n = 8). *(P < 0.05) and **, P < 0.01 indicates significant differences as compared to SRC-3+/+ mice.