Table 4.
Detailed results for hot-spot predicted residues (NIP ≥ 0.4) with available experimental data.
| Complex | Number of predicted residues(NIP ≥ 0.4) | hot-spot prediction success(PPV) | Number of near-native posesa |
| 1BRS | 5 | 100% | 25 |
| 1BXI | 6 | 67% | 6 |
| 1DFJ | 3 | 100% | 8 |
| 1DN2 | 1 | 100% | 5 |
| 1F47 | 3 | 67% | 1 |
| 1JCK | 7 | 100% | 0b |
| 1JRH | 2 | 50% | 10 |
| 1NMB | 1 | 100% | 0c |
| 1VFB | 9 | 67% | 1 |
| 3HFM | 3 | 100% | 0d |
| 1IAR | 7 | 71% | 1 |
| 1AIE | 4 | 50% | 3 |
a Number of near-native solutions (RMSD ≤ 10 Å) within the ensemble of 100 lowest-energy docking orientations used to calculate the NIP values; bbest RMSD within the ensemble is 22.0 Å; cbest RMSD is 20.9 Å; dbest RMSD is 12.2 Å.