Table 1 Patient demographics and presentation details for the case reports included in the present review.
Authors | Drug | Dose (mg) | Sex | Weight (kg) | Age (years) | Other agents taken at time of overdose | Comorbidity | ECG findings prior to CPB |
---|---|---|---|---|---|---|---|---|
Holzer et al (1999)6 | Verapamil | 4800–6400 | M | 60 | 41 | 1 g diclofenac, 1 g thiamine, 5 mg vitamin B12, 6.25 mg timolol; unknown quantity of vitamin B6 | None | Idioventricular escape rhythm, PEA |
Corkeron et al (1999)4 | Flecainide | 4000 | F | Not given | 20 | Alcohol, unknown amount of paracetamol | Asthma, PSVT | Broad complex tachycardia, PEA |
Berhinger et al (1998)7 | Digoxin | 10 | M | Not given | 79 | Nil | Not given | Idioventricular escape rhythm, fast atrial fibrillation, PEA |
Yasui et al (1997)5 | Flecainide130 | Unknown | F | Not given | 20 | Nil | Not given | Idioventricular escape rhythm, agonal rhythm |
Hendren et al (1989)9 | Verapamil SR | 1440 | M | 13.5 | 2 | Nil | None | First degree heart block, third degree heart block |
Pasic et al (2000)18 | Prajmalium bitartrate | 320 | F | Not given | 25 | Nil | Not given | Bradycardia, PEA, ventricular fibrillation |
Long et al (1989)21 | Bupivacaine | 75 | F | 27 | Nil | None | Ventricular fibrillation |
F, female; M, male; PEA, pulseless electrical activity; PSVT, paroxysmal supraventricular tachycardia; SR, slow release.