Figure 4. UV-induced point and frameshift mutagenesis and spontaneous mutagenesis.

A. Induced point mutagenesis in BY4741 background: wildtype, anc1Δ and rev3Δ cells were exposed to UV doses as indicated. Results are mean of two replicates, +/−SD. B. and C. Induced frameshift mutagenesis in CG379-A₁₂ and CG379-A₁₄ backgrounds: WT and anc1Δ frameshift reversions to a functional Lys2 gene. Cells were exposed to UV doses as indicated. Results are mean of two replicates, +/−SD. D. Spontaneous point mutagenesis, +/−SD, measured as described in Materials and Methods. E. Spontaneous expansion in (CAG)₂₅ repeats, +/−SD, measured as described in Materials and Methods.