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. 2008 Jul 15;93(10):4119–4125. doi: 10.1210/jc.2007-2633

Figure 2.

Figure 2

A–D, RT-PCR showing MEG3 RNA expression in all cases of functioning pituitary adenomas (A, GH-secreting tumors; B, PRL-secreting tumors; and C, ACTH-secreting tumors) and normal human pituitaries (D). Some prolactinomas have a weaker expression (in two cases) (B). E, No MEG3 RNA is detected in any of the 17 clinically nonfunctioning tumors (NFT). C, Negative control without cDNA template; NP, positive control with normal pituitary cDNA. F, Northern blot showing MEG3 RNA expression in a normal human pituitary (lane 1), 2 GH-secreting tumors (lanes 7 and 8), and a PRL-secreting tumor (lane 9), but not in five clinically nonfunctioning tumors.