Figure 5.

Concentration–response curves to histamine (a), 5-HT (b) and dopamine (c) in the absence and presence of mepyramine (a), ketanserin and methiothepin (b) or haloperidol (c) constructed in arterial rings with intact endothelium. Data are means±s.e.mean from four to nine separate experiments, expressed as a percentage of the response to 60 mM KCl. When no error bar is shown, the error is smaller than the symbol. ^**P<0.01 and ^***P<0.001 indicate significant differences between histamine, 5-HT or dopamine in the presence and absence of their respective antagonists.